Increased amputation risk with sglt2 inhibitors

https://www.medpagetoday.com/Endocrinology/Diabetes/65331

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Dr. Sandeep Tak

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Dr Sandeep Tak MBBS, MD (AIIMS), CCST eq (UK). Professor of Medicine, S N Medical College, Jodhpur(India). Consultant Physician &Diabetologist. Clinic Address:38B, West Patel Nagar, Circuit House Road, Jodhpur. click on link below for directions: https://www.google.co.in/maps/dir/''/sandeep+tak/@26.28171,72.9658897,12z/data=!3m1!4b1!4m8!4m7!1m0!1m5!1m1!1s0x39418c56c63c0069:0xa8ecc1c5a2dd1232!2m2!1d73.03593!2d26.281727 For appointment call: 9461134057(after 11am.- Sunday closed) Blogs: http://diabetescareindia.blogspot.in/ (Diabetes Education for Diabetics) http://saynototobacco.blogspot.in/ (Anti Tobacco blog) Member: American Academy of Clinical Endocrinologist, Research Society of Diabetes in India, Indian Rheumatology Association, Association of Physicians of India. Publications & Research: Tak S, Ahluwalia G, Sharma SK, Mukhopadhyaya S, Guleria R, Pande JN. Hemoptysis in patients with a normal chest radiograph: Bronchoscopy-
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  Association of C-peptide level with peripheral neuropathy in type 2 diabetes: An observational cross-sectional preliminary study Umaid Potaliya, Sandeep Tak, Manish Goyal Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 17, Issue 2, 2023, 102725, ISSN 1871-4021, https://doi.org/10.1016/j.dsx.2023.102725. https://www.sciencedirect.com/science/article/pii/S1871402123000218 Abstract:  Backround and aims Peripheral neuropathy is the most common microvascular complication of diabetes mellitus. In subjects with type 1 diabetes (T1D) relationship of C-peptide levels and neuropathy has been observed in several studies, however, there are very few studies in type 2 diabetes (T2D) subjects. In this study we aim to assess the association of C-peptide levels with peripheral neuropathy in Indian subjects with T2D. Method One hundred patients of T2D were included in this study. Clinical and laboratory parameter was assessed for all participants. The C-peptide level was me
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  Early-Onset Type 2 Diabetes, and Mood, Anxiety, and Stress-Related Disorders   Prevalence of type 2 diabetes (T2D) has been on rise for decades, and so is trend for patients getting it at younger age. The earlier onset of T2D is more challenging for patients as well as healthcare providers. The prevalence of psychiatric disorder  is known to be higher in T2D subjects however, its prevalence in early-onset T2D is not well studied. Also T2D and psychiatric illnesses are know to cluster in family and close relatives.   In an interesting population-based cohort study  done by Liu et al 1, that  included individuals born in Sweden during 1968–1998. They identified pairs of full siblings, half-siblings, cousins and obtained information on diagnoses of early-onset T2D (< 45 years age) and mood disorders ( unipolar depression/ bipolar disorder), anxiety, and stress-related disorders from the National Patient Register.    In this study over 3 million persons were studied and 0.3% with  ear
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